The IX Nations Super Saturday begins in Cardiff, where Wales will be hoping to end a difficult campaign in style against lowly Italy.
Wayne Pivac’s side never looked capable of defending their title in an injury-riddled Championship, with only one victory – a narrow triumph over Scotland – on their record and many question marks over the future direction of Welsh rugby.
To their credit, Wales fought valiantly in the second half against England and against Grand Slam champions France in the fourth round, but with no results to show.
That will surely change against Italy, who produced their own late show against Scotland in Rome last weekend but once again have the wooden spoon guaranteed.
The Azzurri have yet to win a Six Nations game since 2015, a run of 36 successive defeats which has once again intensified calls for them to be replaced or relegated.
Wales vs Italy kick off date, time and venue
Wales v Italy is scheduled to kick off at 2.15pm GMT on Saturday 19th March 2022.
The game will take place at the Principality Stadium in Cardiff.
How to watch Wales v Italy
TV channel: In the UK, Wales v Italy will be shown live on BBC One, with coverage starting at 1.45pm.
Direct: Live coverage of the match will also be available online, via the BBC Sport website and BBC iPlayer.
Wales vs Italy Team News
Pivac makes seven changes to the side narrowly beaten by France, with influential captain Alun Wyn Jones returning from injury to earn his 150th cap and Dan Biggar joining the Centurions list.
In defense, Gareth Davies, Uilisi Halaholo, Johnny McNicholl and Louis Rees-Zammit all come in, with Dewi Lake and Dillon Lewis promoted to the pack.
Liam Williams, Alex Cuthbert, Jonathan Davies, Tomos Williams, Ryan Elias, Tomas Francis and Will Rowlands all make their mark.
For Italy, Ange Capuozzo makes his first full-back start after a late double on his debut from the bench against Scotland, while Marco Fuser comes second.
Edoardo Padovani switches to the right wing, Pierre Bruno being ruled out through injury. Fuser replaces Niccolo Cannone.
Braam Steyn is ready for his 50th cap from the bench.
The compositions of Wales against Italy
Composition of Wales: McNicholl; Rees-Zammit, Watkin, Halaholo, Adams; Biggar, G Davies; Thomas, Lake, Lewis, Beard, AW Jones, S Davies, Navidi, Faletau.
Replacements: Roberts, W Jones, L Brown, Rowlands, Moriarty, Hardy, Sheedy, Tompkins.
Italy composition: Angel Capuozzo; Edoardo Padovani, Juan Ignacio Brex, Leonardo Marin, Montanna Ioane; Paolo Garbisi, Callum Braley; Danilo Fischetti, Giacomo Nicotera, Pietro Ceccarelli, Marco Fuser, Federico Ruzza, Giovanni Pettinelli, Michele Lamaro, Toa Halafihi.
Replacements: Luca Bigi, Cherif Traore, Tiziano Pasquali, David Sisi, Niccolò Cannone, Braam Steyn, Alessandro Fusco, Marco Zanon.
Wales vs Italy Prediction
Wales have named a very different line-up, although the return of skipper Jones for his incredible latest milestone will give the whole stadium and squad a real boost.
It was an unforgettable campaign for the hosts, but they will imagine their chances of finishing with an emphatic victory.
Despite flashes of promise and progress under New Zealander Kieran Crowley, it was another long tale of woe for the Azzurri in the Six Nations.
Another heavy loss undoubtedly lies ahead.
Wales win by 15 points.
Wales vs Italy head to head (h2h) history and results
Wales have won each of the last 16 matches between these two nations, with Italy’s last success being in Rome at the 2007 Six Nations thanks to Mauro Bergamasco’s late try.
They also beat Wales in the 2003 edition, while winning an 18 draw at Cardiff in 2006.
Wales vs Italy Odds
Wales winner: 1/100
Italy win: 25/1
Odds via Betfair (subject to change).