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NFL pick, Week 6 forecast: Browns inflict first loss on Cardinals;  Chargers, bills, buccaneers stay hot


The NFL season enters Week 6 and there are five clashes between the teams with winning records.

1 p.m. ET features the renewed NFC North rivalry between the Packers and Bears, which will give rookie quarterback Justin Fields his first start in the series. The fiery Chargers also face the Ravens in a clash between Justin Herbert and Lamar Jackson.

The 4 p.m. ET slot also features two exciting games. AFC West surprises Las Vegas and Denver face off in a battle of teams trying to keep pace in the division, and Heisman Trophy winners Kyler Murray and Baker Mayfield face off in a game between the Cardinals and the Browns .

Buffalo ends the week with a trip to Tennessee on Monday Night Football. It’s a roster full of potential playoff clashes, and these games won’t be easy to pick.

Each week, Sporting News will select matches directly. Here’s a look at our season totals:

With that in mind, here are our picks and predictions for week 6:

NFL POWER RANKS:
Bills, Cowboys, Chargers serious contenders; Chiefs and 49ers drop out for week 6

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NFL predictions for week 6

  • Tampa Bay Buccaneers (-7) vs. Philadelphia Eagles

Thursday, 8:20 p.m., FOX / NFL Network

Remember Tom Brady’s inexplicable “Thursday Night Football” loss to the Bears last year? Yes, he probably does too. The Eagles rank third in the league in pass defense (194.8) and protect the ball well, but Brady will press them with a top-flight offense.

To take: Buccaneers 31, Eagles 21

  • Miami Dolphins (-3.5) vs. Jacksonville Jaguars

Sunday, 9:30 a.m., CBS

The Jaguars will hear about a 20-game losing streak all the way to London. Both defenses allow more than 30 points per game, and the Jaguars have the worst turnover differential in the league. If Jacksonville quarterback Trevor Lawrence is going to win his first start, then it might as well be in the most unlikely place.

To take: Jaguars 30, Dolphins 27

  • Green Bay Packers (-4.5) vs. Chicago Bears

Sunday, 1 p.m., FOX

Fields will make his first start against the Packers. Aaron Rodgers is 21-5 against the Bears, and that includes four straight wins. If Fields wants to be loved by the fan base, then this is the game to do it. The Bears have a statistical top 10 defense, but so do the Packers. A few turnovers made up for Green Bay’s slow start on the road.

To take: Packers 28, Bear 20

NFL pick, Week 6 forecast: Browns inflict first loss on Cardinals;  Chargers, bills, buccaneers stay hot
(Getty Images)

  • Cincinnati Bengals (-3.5) vs. Detroit Lions

Sunday, 1 p.m., FOX

The Lions lost two games on last-second baskets. The Bengals are 2-2 in four games decided by three points. This Joe Burrow (throat contusion) status will need to be monitored throughout the week, and Cincinnati needs to show a greater commitment to the racing game. Look for the Bengals to win another close game to split their NFC North section of the calendar.

To take: Bengals 24, Lions 21

  • Houston Texans vs. Indianapolis Colts (-10)

Sunday, 1 p.m., CBS

The Colts are double-digit favorites at home after five straight weeks as an underdog. Houston is 3-2 ATS as an underdog this season, and they catch the Colts in a short week. This match will be closer than expected.

To take: Colts 29, Texans 22

  • Los Angeles Rams (-10.5) vs. New York Giants

Sunday, 1 p.m., FOX

The Rams roll with an offense that averages the second-most passing yards at 310.2 yards per game. Sean McVay could also put more emphasis on the running game, especially against a Giants team that deals with injuries with star offensive players Daniel Jones, Saquon Barkley and Kenny Golladay.

To take: Rams 35, Giants 18

NFL pick, Week 6 forecast: Browns inflict first loss on Cardinals;  Chargers, bills, buccaneers stay hot
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  • Kansas City Chiefs (-6.5) at Washington Football Team

Sunday, 1 p.m., CBS

It’s supposed to be a good game for the Chiefs, but they can’t take it for granted on the road in Washington. The good news is Washington has allowed 35.3 points per game and generated just two turnovers in the past three weeks. Kansas City remains patient and Patrick Mahomes brings them down to 0.500.

To take: Chiefs 34, Washington 24

  • Minnesota Vikings vs. Carolina Panthers (-1.5)

Sunday, 1 p.m., FOX

Which shift do you trust the most? Sam Darnold has six touchdown passes and six interceptions. Kirk Cousins ​​has 10 touchdowns and two interceptions. Backers Dalvin Cook and Christian McCaffrey could come back for this one, but it’s a question of which quarterback can avoid this costly mistake.

To take: Vikings 25, Panthers 22

  • Los Angeles Chargers vs. Baltimore Ravens (-3.5)

Sunday, 1 p.m., CBS

It’s the most exciting game of the first window, a battle between star quarterback Justin Herbert and Lamar Jackson. It’s an early kick for a West Coast team, and it’s something to be aware of. But Los Angeles is doing fantastic 3-0 on the road.

To take: Chargers 30, Ravens 27

NFL pick, Week 6 forecast: Browns inflict first loss on Cardinals;  Chargers, bills, buccaneers stay hot
(Getty Images)

  • Arizona Cardinals vs Cleveland Browns (-2.5)

Sunday, 4:05 p.m., FOX

The Cardinals and Browns both have elite offenses, and former Oklahoma Heisman winners Kyler Murray and Baker Mayfield will put on a show. What defense can stop in times of crisis? Murray won the last head-to-head in 2019, and the Cardinals have won the last four in the series. This one is in Cleveland, however, and the Browns eliminate the last undefeated team.

To take: Brown 33, Cardinals 28

  • Las Vegas Raiders vs. Denver Broncos (-3)

Sunday, 4:25 p.m., CBS

The Raiders and Broncos are both stuck in two-game slips after a 3-0 start, and it’s an important game to keep pace in the AFC West race. The Raiders swept that streak last season, and Derek Carr is getting the passing offense back on track on the road.

To take: Raiders 26, Broncos 24

  • Dallas Cowboys (-4) vs. New England Patriots

Sunday, 4:25 p.m., CBS

The Cowboys are starting to get a bit of a hype with a balanced attack around Dak Prescott. Dallas has run over 200 yards in the past two weeks. The Pats are fifth in the NFL in scoring defense and will try to curb that momentum, but New England will fall to 0-4 in home games this season.

To take: Cowboys 23, Patriots 20

NFL pick, Week 6 forecast: Browns inflict first loss on Cardinals;  Chargers, bills, buccaneers stay hot
(Getty Images)

  • Seattle Seahawks vs. Pittsburgh Steelers (-4.5)

Sunday, 8:20 p.m., NBC

Geno Smith is taking over for the Seahawks, and it’s a tough task facing a Pittsburgh defense that has increased the pass rush over the past two weeks with the return of TJ Watt. The Steelers return to .500 with another effective performance from Ben Roethlisberger.

To take: Steelers 26, Seahawks 18

  • Buffalo bills (-4.5) against the Tennessee Titans

Monday, 8:15 p.m., ESPN

The Bills have a case as the best football team, but it’s a delicate clash. Remember Derrick Henry’s legendary stiff arm last year? It was in a 42-16 win over Buffalo. Tennessee are still trying to get Julio Jones back, and that could set up an exciting AFC shootout. We’re not betting against Josh Allen after making this mistake last week.

To take: Tickets 35, Titans 31





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