The 33-year-old former Chelsea midfielder has one year left on his contract at Old Trafford but has indicated his intention to leave the club at the end of the season after talks with the board, team-mates and interim coach Ralf Rangnick.
It remains to be seen whether United will pursue a transfer for Matic, or whether the club – who have agreed in principle for Ajax boss Erik ten Hag to take over the coaching reins next season – have intention to agree to an early termination of the three-year extension he signed in July 2020.
Writing on Instagram on Friday, Matic said: “After careful consideration I have decided that this season will be my last with Manchester United. I have informed the board, manager and players of my decision.
“It was a huge honor and privilege to play for this great club. Many thanks to the fans for their unwavering support.
“I will now give everything until the end of the season to help my teammates finish as strong as possible.”
Matic has made 183 total appearances for United in all competitions since joining from Premier League rivals Chelsea in a £40m deal in the summer of 2017.
He failed to win a single major trophy in his five years as the Red Devil, being part of the side that lost the 2017-18 FA Cup final to Chelsea and the League final Europa 2020-21 against Villarreal.