The Red Devils salvaged a 1-1 draw in their last round of 16 trip to Atletico Madrid on Wednesday night after the teenager’s late goal came on as a 75th-minute substitute.
Ralf Rangnick has a decision to make on whether to start Elanga ahead of Jadon Sancho or Marcus Rashford, the latter having struggled for form in recent weeks.
Edinson Cavani is again set to miss Saturday’s 3pm kick-off at Old Trafford as he recovers from a groin problem.
Scott McTominay could return for United, however, after a bout of illness kept him out of Madrid. Mason Greenwood continues to be unavailable for selection.
On Friday, Rangnick will provide a further update on how his side have recovered from the Atletico draw when he faces the media.
Man United predicted XI: De Gea; Dalot, Varane, Maguire, Telles; Fred, Pogba; Elanga, Fernandes, Sancho; Ronaldo.