The points were shared in a thrilling 2-2 draw when the title contenders met at Anfield in October and only one point separates the sides ahead of this clash.
While Liverpool have fought hard to close the gap to the defending champions, neither side come into the clash at the Etihad Stadium in anything but great form.
City beat Atletico Madrid in midweek to win four in a row and eight unbeaten, while Liverpool’s victory at Benfica gave them five straight wins with their last league loss in December.
Here’s everything you need to know ahead of the game…
Date, kick-off time and venue
Manchester City vs Liverpool is scheduled to kick off at 4.30pm BST on Sunday 10 April 2022.
The Etihad Stadium in Manchester will host the match.
Where to watch Manchester City v Liverpool
TV channel: The match will be televised on Sky Sports Premier League and Main Event, with coverage starting at 4pm.
Direct: Sky Sports subscribers will be able to watch the match online via the Sky Go app.
Live Blog: You can follow all the action via Standard Sport’s live blog.
Manchester City vs Liverpool Team News
Ruben Dias is the conspicuous absentee on both sides as managers prepare to choose from largely in-form squads.
A hamstring problem continues to keep the City defender out of action, although Kyle Walker is expected to return to the line-up following his European ban.
Trent Alexander-Arnold has recovered from injury to feature for Liverpool against Benfica in midweek as Jordan Henderson pushes for a departure.
Manchester City vs Liverpool Prediction
This one is so hard to call. In City’s favour, they have a great record against Liverpool, are at home and just have this weird talent to pull through in those games even when they’re not in top form.
In Liverpool’s favour, their goalscoring form is terrific, they too are on a roll and Jurgen Klopp’s side seem highly motivated to reclaim the title. But – City are the favourites.
A 2-1 win for Man City.
Head-to-head history and results (h2h)
Liverpool have not won a league game at the Etihad since 2015, winning in their last eight meetings in total.
Man City win: 58
Liverpool win: 105