Ronaldo remains keen to leave the club this summer and stayed away for the entire first week under new manager Erik ten Hag as he tried to arrange a move to no avail. Now he has to play in front of the home support for the first time since the end of last season.
The Portuguese was not included in the squad that lost 1-0 to Atletico Madrid on Saturday but starts as a second-string side at Old Trafford this afternoon.
Raphael Varane is the team’s captain and sits alongside debutant Lisandro Martinez in defence. Elsewhere, Christian Eriksen features again after his appearance against Atletico Madrid, while Donny van de Beek is given a rare chance to impress.
CLICK HERE TO FOLLOW MAN UNITED VS RAYO VALLECANO LIVE!
Manchester United starting line-up: Heaton; Laird, Martinez, Varane, Telles; van de Beek, Garner, Chong; Eriksen, Ronaldo, Garnacho