After the Reds’ Carabao Cup final triumph over Chelsea, which lasted 120 minutes and saw all eleven players kicked out, the German boss could be forgiven for fielding a weaker side at Anfield.
Liverpool have not had a midweek break since late January and will face crucial games with West Ham, Inter Milan, Arsenal and Manchester United ahead of the next international break.
Therefore, Klopp will give Divock Origi, Curtis Jones and Alex Oxlade-Chamberlain chances in the fifth round.
Thiago Alcantara is out after his late withdrawal from the Carabao Cup starting line-up, which led to the midfielder watching from the Wembley touchline in tears.
Klopp said on Tuesday: “He’s fine again. But not in good shape. It’s not clear how long [he will be out]. For the weekend, not sure. Milan perhaps? But after that, definitely.
Diogo Jota passed a late fitness test to make the bench on Sunday while Roberto Firmino missed.
Liverpool predicted XI: Keller; Bradley, Gomez, Konaté, Tsimikas; Jones, Milner, Elliott; Minamino, Oxlade-Chamberlain, Origi.