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German scientist believes he has found solution to blood clots linked to AstraZeneca, Johnson & Johnson COVID-19 vaccines


AstraZeneca vaccine. Mario Tama / Getty Images

Rolf Marschalek, professor at Goethe University in Frankfurt, Germany, claims to have identified the cause of rare blood clots linked to COVID-19 vaccines developed by Johnson & Johnson and the University of Oxford and AstraZeneca. Subsequently, he also believes he has found a way for the growers to change their plans so that the clots do not occur again, The Financial Times reports.

Marschalek said his research focused on vaccine adenovirus vectors, which “send the spike protein into the cell nucleus rather than the cytosol fluid inside the cell where the virus normally produces proteins.” (The Pfizer-BioNTech and Moderna vaccines, on the other hand, do not enter the nucleus.) The theory is that once the spike protein enters the nucleus, some parts splice and create mutant versions, FT reports. In theory, these mutant proteins are then “secreted by cells in the body” where they can trigger life-threatening blood clots.

The research, argues Marschalek, suggests that vaccine developers could “alter the sequence of the spike protein” so that it does not separate. He said Johnson & Johnson had already contacted his lab “to seek advice,” although other scientists urge patience. “This is yet another hypothesis that needs to be proven by experimental data,” said Johannes Oldenburg, professor at the University of Bonn in Germany. FT. Read more on The Financial Times.



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