For both children and adults, there are hard-to-swallow pills.
A team of researchers from MIT and Brigham and Women’s Hospital believe they have solved this problem with a gel made from vegetable oils, such as sesame.
This gel can be made in a variety of different textures, ranging from a “thickened drink” to a yogurt-like substance, according to an MIT News Office article.
“This platform will change our ability to do what we can do for children, but also for adults who have difficulty receiving medication. Given the system’s simplicity and low cost, it could have a huge impact in making it easier for patients to take medication,” said Giovanni Traverso, gastroenterologist at Brigham and Women’s Hospital and lead author of the study. on the frost.
During the process of finding the right set of ingredients for the gel, the researchers tried vegetable oils such as sesame, cottonseed, and flaxseed. These have been combined with certain types of “edible gelling agents” such as beeswax or rice bran wax.
Through this process, the researchers discovered the different potential textures of the gel. The gel can also be stored unrefrigerated and can therefore be used in regions that this type of technology would not normally reach.
To make sure the gels tasted good enough for the masses, the researchers worked with consulting firm Sensory Spectrum and trained panels of tasters to come up with a combination of oils that had the most appealing flavor.
The researchers chose to test this gel with drugs that prevent diseases such as malaria, parasites and bacterial infections.
“Based on this list, infectious diseases really stood out in terms of what a country needs to protect its children,” said Ameya Kirtane, a teacher at Brigham and Women’s Hospital and lead author of the study.
The researchers have now obtained FDA approval to conduct a Phase I clinical trial for one of their gel formulas which they hope to conduct at the Brigham and Women’s Hospital Center for Clinical Investigation in the coming months.
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