Kovacic was on the bench for Everton on opening day but has struggled with a persistent knee problem throughout the summer which will see him miss this afternoon’s Capital clash.
Alonso, meanwhile, is also ruled out due to an impending move to Barcelona which has seen him train alone at Cobham.
“He (Alonso) is not in training at the moment and is trying to finalize his transfer so he won’t be available for the game,” Chelsea boss Thomas Tuchel said on Friday. “It’s the same for Kova, who is injured.
“He has problems with his knee, always a little reaction. We decided to take a step back and increase the treatment time to reduce the stress that comes from training to have a normal reaction before starting again. Everyone world is available.”
Chelsea are expected to field a very similar formation to the one that won 1-0 at Goodison Park last Saturday thanks to Jorginho’s penalty late in the first half.
A big decision will be about Ben Chilwell’s fitness and whether to continue using him, despite his ongoing recovery from a serious knee injury.
Marc Cucurella could be in line for his first start and home debut in west London. Raheem Sterling and Kalidou Koulibaly will both make their home debuts against Tottenham.
Predicted Chelsea XI: Mendy; Azpilicueta, Thiago Silva, Koulibaly; James, Kante, Jorginho, Cucurella; Mount, Havertz, Sterling