Arteta made 10 changes for Wednesday’s 3-1 home loss to Brighton, with only William Saliba keeping his place since the win over Chelsea.
The Gunners boss returns to this Stamford Bridge side for tonight’s trip to Molineux, which Arsenal are hoping to win so they top the Premier League on Christmas Day.
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The only doubt for Arsenal ahead of the game was full-back Takehiro Tomiyasu, who is suffering from a muscle injury after limping against FC Zurich in the Europa League last week. He completely misses the team.
Oleksandr Zinchenko is back at left-back, with Kieran Tierney on the bench, while the usual front three of Gabriel Jesus, Gabriel Martinelli and Bukayo Saka all start.
Arsenal XI: Ramsdale, White, Saliba, Gabriel, Zinchenko, Partey, Xhaka, Odegaard, Saka, Jesus, Martinelli.
Subtitles: Turner, Tierney, Nketiah, Holding, Cédric, Vieira, Nelson, Elneny, Marquinhos.
Saturday 7:45 p.m. GMT, Sky Sports